Liquid dose forms are a common and widely used way to solve the many problems of giving medicines to children, the elderly, and animals. However, instabilities like sedimentation, flocculation, and caking – especially in suspensions – make it hard to develop new formulations. It solves these problems by allowing a customized balance of rheological qualities to provide high content uniformity and long-term stability in suspensions without adding a lot of viscosity.
It is a one-of-a-kind suspending and emulsifying ingredient that makes a variety of liquid dosage forms possible. Our product may be used with a wide range of active pharmaceutical ingredients (APIs) because of its stabilizing function, allowing for new applications and line expansions for current products.
It may be combined with a wide range of active pharmaceutical ingredients (APIs), allowing new applications and product line expansions. Our VIVAPUR MCG is used in the following applications as a suspending agent, emulsifier, opacifier, and thickener:
High viscosity cannot ensure reliable particle stability in a suspension since it just slows down settling. MARK-VIVAPUR MCG is a versatile thickener. It creates a three-dimensional elastic gel network of insoluble cellulose fibrils after activation in water, forming a yield point. The minimal shear stress necessary to commence flow is known as the yield point. If the force of gravity acting on the particle mass does not exceed the liquid’s yield point, the suspension is stable. All particles may be retained homogeneously and prevented from settling within the supportive network.
MCG dispersions lose their viscosity and become liquid when agitated in a time and shear-dependent manner. The following rest interval allows for complete, time-dependent regeneration of viscosity. This so-called “thixotropic behavior” allows you to do things like: