Crospovidone is a tablet lubricant explicitly created for formulations where alternative lubricants cause formulation and/or manufacturing issues. MARK-PRUV has the following advantages over the commonly used lubricant magnesium stearate:
No influence on the dissolution
Resistance to over lubrication
Improved appearance of effervescent solutions
High API compatibility
Azathioprin, Cefaclor, Cilazapril, Clopidogrelacetate, Diclofenac, Fosinopril, Ibuprofen, Ketorolac, Levofloxacin, Nifedipine, Omeprazole, Ramipril, and Trandolapril are some of the APIs that have been found to have incompatibility issues with magnesium stearate.
It aids in creating new products and is especially well suited for high-speed direct compression of tablets.